Sodium Bicarbonate in Cancer Treatment: A Promising Ally Against Tumor Acidity” v1
Introduction
Cancer remains a formidable adversary, affecting millions of lives worldwide. Researchers continually explore novel approaches to improve treatment outcomes. One such avenue of investigation involves the use of sodium bicarbonate, commonly known as baking soda. In this article, we delve into the antitumor effects of sodium bicarbonate, its constructive functions, and the ongoing clinical research.
1. Antitumor Effects
The Acidic Tumor Microenvironment
Tumors often create an acidic microenvironment due to their rapid growth and metabolism. This acidity can promote cancer progression and resistance to treatment. Sodium bicarbonate, with its alkaline properties, aims to neutralize this acidity.
Clinical Trial: TILA-TACE
In the groundbreaking clinical trial called targeting intratumor lactic acidosis–transarterial chemoembolization (TILA-TACE), researchers modified the standard chemoembolization procedure. They added a 5% sodium bicarbonate solution to cytotoxic drugs (such as doxorubicin or oxaliplatin). The results were remarkable: 100% of patients treated with this modified TACE achieved complete or partial remission.
2. Constructive Functions of Cancer Cells
While cancer cells are primarily harmful due to their uncontrolled growth and invasion, some aspects of their behavior can be considered “constructive” in specific contexts:
- Angiogenesis: Cancer cells can stimulate healthy cells around them to grow new blood vessels. This process supplies nutrients to tumors, allowing them to thrive.
- Tumor Microenvironment: Each tumor is a complex mixture of different cell types. By studying cancer cells individually, researchers gain insights into treatment resistance and potential therapeutic targets.
3. Safe and Effective Use
While sodium bicarbonate shows promise, it’s crucial to use it safely and effectively. Consult with healthcare professionals before incorporating it into any treatment plan.
